Florfenicol CAS Naj Npawb: 73231-34-2 Molecular Formula: C12H14Cl2FNO4S
2,2-dichloro-n-[(1r,2s)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamide
AQUAFEN FLORFENICOL NUFLOR
[r-(r*, r*)]-n-[1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulforyl)phenyl)-ethyl]-2,2-dichloroacetamide
[R-(R*,S*)]-2,2-DICHLORO-N-[1-(FLUOROMETHYL)-2-HYDROXY-2-[4-(METHYLSULFONYL)PHENYL]ETHYL]acetamide
SCH-25298
(r-(r*,s*))-methyleste
2,2-dichloro-n-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl
4-(2-((dichloroacetyl)amino)-3-fluoro-1-hydroxypropyl)-benzenesulfonicaci
Florfeniol
FLUPROFEN
Fluorothiamphenicol
Sch-25298, Aquafen
Acetamide, 2,2-dichloro-N-(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-4-(methylsulfonyl)phenylethyl-
2,2-Dichloro-N-[(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide
Aquaflor
Aquafen, Nuflor, SCH-25298, [R-(R*,S*)]-2,2-Dichloro-N-[1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl ] acetamide
2,2-Dichloro-N-(1-(fluoromethyl)-2-hydroxy-2-(4-(methylsulfonyl)phenyl)ethyl)acetamide
2,2-Dichloro-N-[(1R,2S)-3-fluoro-1-hydroxy-1-(4-methylsulfonylphenyl)propan-2-yl]acetamid
| Melting Point | 153° Nws |
| Qhov ntom | 1.451 ± 0.06 g / cm3 (Predicted) 1.1782 (kwv yees ntxhib) |
| cia temp | 2-8 ° C |
| solubility | Soluble hauv ethanol rau 25mM thiab hauv DMSO rau 100mM |
| kev ua haujlwm kho qhov muag | N/A |
| Qhov tshwm sim | Dawb rau Off-White |
| Purity | ≥98% |
Florfenicol yog ib tug dav-spectrum fluorinated tshuaj tua kab mob thiab ib tug derivative ntawm thiamphenicol (khoom No. 21357).Nws yog nquag tawm tsam tib neeg kev soj ntsuam cais ntawm cov kab mob enteric, xws li E. coli, Klebsiella, Enterobacter, Citrobacter, P. mirabilis, thiab Salmonella (MIC).50s = 6.3-12.5 μg / ml).Florfenicol tseem muaj zog tiv thaiv kev soj ntsuam cais ntawm ntau yam kab mob bovine thiab porcine ua pa kab mob, suav nrog P. multocida, A. pleuropneumoniae, thiab B. bronchiseptica (MIC).50s = 0.25-4 μg / ml).Nws inhibits peptidyl transferase kev ua haujlwm hauv 70S ribosomes cais los ntawm E. coli thaum siv ntawm qhov concentration ntawm 1 mM.Cov tshuaj uas muaj florfenicol tau siv los kho cov kab mob ua pa hauv cov nyuj.
Nws yog ib hom tshuaj tua kab mob.Nws yog siv los ua cov tshuaj tua kab mob veterinary rau kev kho cov kab mob kab mob ntawm npua, qaib thiab ntses.Nws muaj txiaj ntsig zoo hauv kev kho tus kab mob ntawm npua, qaib thiab ntses vim yog cov kab mob rhiab heev, tshwj xeeb tshaj yog rau kev kho mob ua pa thiab kab mob hauv plab.
