CAS Naj Npawb: 1115-70-4 Molecular Formula: C4H11N5

Lub molecular pharmacological mechanism ntawm tam sim no tsis to taub tag nrho.Nws paub tias nws ua yam tsawg kawg ntawm daim siab, txo gluconeogenesis (piv txwv li kev tsim cov piam thaj) thiab txo qis cov tshuaj insulin.Qee qhov kev tshawb fawb tau pom tias tuaj yeem ua rau AMP activated protein kinase (AMPK), uas yog ib qho ntawm cov txheej txheem tseem ceeb rau inhibit siab gluconeogenesis thiab txhim kho cov tshuaj insulin hauv cov teeb liab hloov pauv ntawm insulin.AMPK, raws li cov protein kinase, ua lub luag haujlwm tseem ceeb tsis yog nyob rau hauv txoj kev taw qhia cov tshuaj insulin xwb, tab sis kuj nyob rau hauv tag nrho lub zog sib npaug thiab cov piam thaj thiab cov rog metabolism.Kev sim tsiaj txhu thiab kev tshawb fawb soj ntsuam tau pom tias tuaj yeem ua rau muaj kev hloov pauv tseem ceeb hauv cov kab mob fecal microbiota hauv ntshav qab zib mellitus, uas tuaj yeem tsis tsuas yog pab txhawb rau kev tso tawm thiab cov nyhuv ntawm glucagon zoo li peptide-1 (GLP-1), tab sis kuj ua pov thawj los txhim kho cov tshuaj insulin. , uas kuj yog ib qho ntawm cov txheej txheem tseem ceeb ntawm nws cov tshuaj tiv thaiv kab mob ntshav qab zib hom 2.