Orlistat CAS Naj Npawb: 132539-06-1 Molecular Formula: C28H29NO
| Melting Point | 195-200 ° C |
| Qhov ntom | 1.4 g / cm³ |
| cia temp | 2-8 ℃ |
| solubility | insoluble hauv dej, me ntsis soluble hauv ethanol, yooj yim soluble hauv chloroform thiab methanol |
| kev ua haujlwm kho qhov muag | +71.6 (c = 1.0, ethanol) |
| Qhov tshwm sim | dawb los yog dawb crystalline hmoov |
Olistat yog lub sijhawm ntev, tshwj xeeb hauv plab hnyuv lipase inhibitor uas tuaj yeem tiv thaiv hydrolysis ntawm triglycerides rau hauv absorbable fatty acids thiab monoacylglycerols, tiv thaiv lawv los ntawm absorbed, yog li txo calorie kom tsawg thiab tswj qhov hnyav.Thaum siv los ua cov tshuaj tom khw muag khoom noj rau tus kheej, orlistat yog qhov tsim nyog rau kev kho mob ntawm cov neeg rog rog lossis rog rog (nrog rau lub cev qhov ntsuas ntawm ≥ 24 thiab kwv yees kwv yees qhov hnyav / qhov siab 2).
Orlistat yog cov tshuaj poob phaus, ua lag luam raws li Xenical.
Olistat yog saturated derivative ntawm lipstatin.Lipstatin yog ib qho zoo ntawm pancrelipase inhibitor cais tawm los ntawm Streptomyces toxitricini Nws tsuas yog ua rau lub plab zom mov.Nws tuaj yeem cuam tshuam cov enzymes uas xav tau los ntawm txoj hnyuv plab zom mov kom zom cov rog, suav nrog pancreatic ester thiab gastric ester, thiab txo qhov nqus ntawm plab hnyuv ester kom rog los pab kom poob phaus, tab sis nws tseem yuav tsum tau ua ke nrog kev tawm dag zog thiab noj zaub mov kom poob phaus.
Qhov pom zoo npaum li cas rau Olistat capsules yog 0.12g capsules noj nrog zaub mov lossis hauv ib teev tom qab noj mov.Yog tias muaj ib pluas noj uas tsis tau noj lossis yog cov zaub mov tsis muaj rog, ib qho tshuaj yuav raug tshem tawm.Cov txiaj ntsig kho mob ntawm kev siv lub sij hawm ntev ntawm orlistat capsules, nrog rau kev tswj qhov hnyav thiab txhim kho cov kev pheej hmoo, tuaj yeem txhawb nqa.Tus neeg mob cov zaub mov yuav tsum muaj kev noj haus kom zoo, nrog rau cov calories tsawg tsawg.Kwv yees li 30% ntawm calorie ntau ntau yog los ntawm cov rog, thiab cov zaub mov yuav tsum muaj cov txiv hmab txiv ntoo thiab zaub.
