Rifampicin CAS Naj Npawb: 13292-46-1 Molecular Formula: C43H58N4O12

Lus piav qhia luv luv:

Lub npe tshuaj:Rifampicin

Molecular Formula:
C43H58N4O12

Cov ntsiab lus: 9,17,19,21-hexahydroxy-23-methoxy-2,4,12,1///;2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b) furan-1,11(2-h)-dione,5,6;3-((((4-methyl-1-piperazinyl)imino)methyl)-rifamyci;3-(((4-methyl-1-piperazinyl)iminomethyl rifamycinsv; 8-((((4-methyl-1-piperazinyl)imino)methyl)rifamycinsv;8-(4-Methylpiperazinyliminomethyl)rifamycinSV;8-(n-(4-methyl-1-piperazinyl)formidoyl)-rifomycins; RIFAMPIN "LEPETIT"

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Product Detail

Khoom cim npe

Khoom Specification

Melting Point	183° Nws
Qhov ntom	1.1782 (kev kwv yees kwv yees)
cia temp	2-8 ° C
solubility	chloroform: soluble 50mg / mL, ntshiab
kev ua haujlwm kho qhov muag	N/A
Qhov tshwm sim	faint liab mus tsaus liab heev
Purity	≥99%

Kev piav qhia

Rifampicin yog ib tug semisynthetic derivative ntawm rifamicin B, ib tug macrolactam tshuaj tua kab mob thiab ib tug ntawm ntau tshaj tsib tshuaj tua kab mob los ntawm ib tug sib tov ntawm rifamicins A, B, C, D, thiab E, uas yog hu ua ib tug rifamicin complex, uas yog tsim los ntawm actinomycetes Streptomyces mediteranei ( Nocardia Mediteranei).Nws tau nkag mus rau hauv kev kho mob hauv xyoo 1968. Synthesis ntawm rifampicin pib nrog cov tshuaj aqueous ntawm rifamicin, uas nyob rau hauv cov tshuaj tiv thaiv yog oxidized rau ib tug tshiab derivative ntawm rifamicin S (32.7.4), nrog rau nruab nrab tsim ntawm rifamicin O (32.7. 3).Txo cov qauv quinone ntawm cov khoom no nrog hydrogen siv palladium ntawm carbon catalyst muab rifamicin SV (32.7.5).Cov khoom tsim tau dhau los ntawm aminomethylation los ntawm kev sib xyaw ntawm formaldehyde thiab pyrrolidine, muab 3-pyrrolidinomethylrifamicin SV (32.7.6).Oxidizing cov khoom tshwm sim nrog cov hlau lead tetracetate mus rau ib qho enamine thiab tom qab hydrolysis nrog ib tug aqueous tov ntawm ascorbic acid muab 3-formylrifamicin SV (32.7.7).Reacting qhov no nrog 1-amino-4-methylpiperazine muab qhov xav tau rifampicin (32.7.8).

kev siv thiab ntau npaum li cas

Rifampin yog siv los ua tshuaj tua kab mob.Nws yog ib tug semisynthetic derivative ntawm rifamycin B, ib tug macrocyclic tshuaj tua kab mob tsim los ntawm cov pwm Streptomyces Mediterranei.Rifampin yog siv rau kev kho mob tuberculosis, brucellosis, Staphlococcus aureus, thiab lwm yam kab mob sib kis.