CAS Naj Npawb: 21187-98-4 Molecular Formula

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CAS nr: 21187-98-4

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Cov roj formula: C15H21N3O3S

Synonyms: BP;)-4-methyl-;1-(3-azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea;1-(hexahydrocyclopenta(c)pyrrol-2(1h) )-yl)-3-(p-tolylsulfonyl)-urea; 1-(hexahydrocyclopenta(c)pyrrol-2(1h)-yl)-3-(p-tolylsulfonyl) urea; benzenesulfonamide,n-(((( hexahydrocyclopenta(( hexahydrocyclopenta()) c) pyrrol-2(1h)-yl)amino)carbonyl;n-(4-methylbenzenesulfonyl)-n'-(3-azabicyclo(3.3.0)oct-3-yl)urea; Tetrabenzyl Voglibose HCl

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Product Detail

Khoom cim npe

Khoom Specification

Melting Point	163-169 ° C
Qhov ntom	1.2205 (kev kwv yees kwv yees)
cia temp	Inert cua, Chav Kub Kub 2-8 ° C
solubility	methylene chloride: soluble
kev ua haujlwm kho qhov muag	N/A
Qhov tshwm sim	Off-White Solid
Purity	≥98%

Kev piav qhia

yog ib qho tshuaj tiv thaiv kab mob hauv qhov ncauj siv rau kev kho mob ntshav qab zib mellitus hom II.Nws belongs rau sulfonylurea chav kawm ntawm insulin secretagogues, uas txhawb nqa β hlwb ntawm lub txiav kom tso tawm insulin.khi rau β cell sulfonyl urea receptor (SUR1), ntxiv thaiv cov ATP rhiab poov tshuaj raws.Yog li, cov poov tshuaj efflux txo qis, ua rau depolarization ntawm β hlwb.Tom qab ntawd cov kab hluav taws xob-nyob ntawm calcium nyob hauv β cell qhib, ua rau muaj kev ua kom calmodulin, uas ua rau exocytosis ntawm insulin muaj cov secretorty granules.Cov kev tshawb fawb tsis ntev los no kuj tau pom tias tuaj yeem txhim kho kev tiv thaiv oxidant thiab nitric oxide-mediated vasodilation hauv ntshav qab zib hom 2 thiab tiv thaiv pancreatic beta-cells los ntawm kev puas tsuaj los ntawm hydrogen peroxide.

kev siv thiab ntau npaum li cas

yog ib qho tshuaj hypoglycemic ntawm qhov ncauj siv los kho cov mob uas tsis yog-insulin-dependent ntshav qab zib mellitus.Kev kho mob ntshav qab zib cuam tshuam nrog kev rog lossis kab mob vascular, rau cov neeg laus uas muaj ntshav qab zib hom 2. Mob ntshav qab zib yog mob ntev (ntev) kev noj qab haus huv uas cuam tshuam rau koj lub cev hloov pauv. zaub mov rau hauv lub zog.txo cov ntshav qabzib los ntawm kev txhawb nqa cov tshuaj insulin los ntawm β-hlwb ntawm islets ntawm Langerhans.