CAS Number: 171599-83-0 Molecular Formula: C 2 2 H 3 0 N 6 O 4 S·C 6 H 8 O 7 = 666.70
| Melting Point | 49-53° Nws |
| Qhov ntom | 1.05 g / cm³ |
| cia temp | txias, qhuav qhov chaw thiab tsis txhob raug lub teeb los yog kub kub |
| solubility | yooj yim soluble hauv ethanol, acetone, ether, benzene thiab methylene chloride, tab sis insoluble hauv dej |
| kev ua haujlwm kho qhov muag | [α]D20 = +61.0° (ethanol tov) |
| Qhov tshwm sim | dawb mus rau lub teeb daj crystalline hmoov |
Thaum lub sij hawm kev sib deev stimulation, cov hlab ntsha parasympathetic, uas tsis yog adrenergic thiab non cholinergic paj (NANC) xaus thiab vascular endothelial hlwb tso nitric oxide (NO) nyob rau hauv qhov kev txiav txim ntawm nitric oxide synthase (NOS).Hauv cov hlab ntsha, cov soluble guanylate cyclase (sGC) feem ntau yog qhib los ntawm NO, thiab sGC ua rau guanosine triphosphate los tsim cGMP.Lub cGMP nyob rau hauv lub corpus cavernosum ntawm noov exerts ib tug muaj zog vasodilator nyhuv los ntawm kev txo cov concentration ntawm Ca2 + nyob rau hauv cov nqaij mos hlwb ntawm lub corpus cavernosum, ua rau kom so ntawm cov nqaij mos hlwb thiab nce ntshav txaus nyob rau hauv lub corpus cavernosum, ua. mus rau erection.Jinyang alkali txo cov qib ntawm degradation ntawm cGMP, yog li khaws cov nyhuv so ntawm cGMP ntawm corpus cavernosum ntawm noov thiab ua rau noov erection.Hauv vivo, cGMP yog degraded thiab inactivated los ntawm PDE5.
Haum rau kev kho erectile kawg (ED) ntawm noov, nws yog zoo rau erectile kawg tshwm sim los ntawm kev siv cov tshuaj antidepressants, antipsychotics, thiab antihypertensive tshuaj, raws li zoo raws li rau erectile kawg tshwm sim los ntawm kev phais los yog raug mob.
Nws tuaj yeem ua rau cov ntsiav tshuaj, tshuaj, tshuaj ntsiav, tshuaj ntsiav, thiab tuaj yeem siv los ua tshuaj cawv, kua hauv qhov ncauj, kas fes, granules, chewable ntsiav tshuaj, lozenges, zom cov pos hniav, thiab lwm yam tshuaj.Rau cov neeg laus, qhov koob tshuaj yuav tsum yog 10-100mg ib hnub, uas tuaj yeem nce lossis txo qis raws li tus neeg siv qhov xwm txheej.Nws yog qhov zoo dua los coj nws ntawm lub plab khoob (tshwj xeeb yog tsis txhob noj nrog cov zaub mov muaj roj ntau), thiab tsis txhob haus cawv ua ntej siv tshuaj yej (noj yuav tsum tsis txhob noj tib lub sijhawm, uas tsis tau txhais hais tias haus cawv tib yam. Lub sijhawm tuaj yeem txo qhov kev ua haujlwm erectile ntawm Viagra).
Lub Sijhawm Ua Haujlwm: Feem ntau cov neeg siv sijhawm li ib teev kom siv tau.Nws raug nquahu kom noj tshuaj li 1 teev ua ntej kev sib deev, nrog rau nws cov teebmeem ntev li 48 txog 72 teev, thiab qee qhov yuav kav ntev li 116 teev.
